TetraBlaster

TetraBlaster

TetraBlaster is a program to blast nucleotide sequences against databases for sequence homology searches. It allows for fast detection of similar sequences by comparing the query to reference sequences with known function or taxonomy. It is commonly used in bioinformatics.
TetraBlaster image
nucleotide sequence-analysis homology-search blast

TetraBlaster: Bioinformatics Tool for Sequence Homology Searchess

A program for detecting similar nucleotide sequences by comparing queries to reference databases with known function or taxonomy, commonly used in bioinformatics.

What is TetraBlaster?

TetraBlaster is a bioinformatics application used to perform sequence similarity searches to identify homologous sequences. It utilizes a heuristic algorithm to rapidly compare a query nucleotide or protein sequence against reference sequence databases such nucleotide (nt/nr), expressed sequence tags (EST), sequence tagged sites (STS), genomic survey sequences (GSS), high-throughput genomic sequences (HTGS), protein data bank (PDB), SwissProt, PIR, PRF, and custom user databases.

Key features of TetraBlaster include:

  • Fast heuristic search algorithms for rapid sequence comparisons
  • Support for BLAST+ executables for nucleotide blastn, blastp, blastx, tblastn, and tblastx searches
  • Automated retrieval of sequences from NCBI databases for up-to-date comparisons
  • Customizable parameters for e-value, word size, match/mismatch scores etc.
  • Filtering of results by length, similarity percentage or annotation
  • Visualization of alignments, sequence descriptions, and genomic context
  • Exporting results to text, HTML, XML formats

By rapidly scanning sequence databases for local alignments, TetraBlaster enables discoveries of sequence motifs, gene families, and functional domains shared between novel and previously characterized genes. It is a useful tool for functional inference, phylogenetic classification, and genomic annotation projects.

TetraBlaster Features

Features

  1. Rapid sequence homology searches
  2. Comparison of query sequences to reference databases
  3. Detection of similar sequences with known function or taxonomy
  4. Supports various sequence file formats
  5. Intuitive graphical user interface
  6. Customizable search parameters
  7. Batch processing of multiple sequences

Pricing

  • Free

Pros

Fast and efficient sequence comparison

Comprehensive reference databases

User-friendly interface

Suitable for both novice and experienced users

Widely used in bioinformatics research

Cons

Limited support for advanced analysis features

Potential for outdated reference databases

May require additional software or resources for more complex analyses


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