TetraBlaster

TetraBlaster: Bioinformatics Tool for Sequence Homology Searchess

A program for detecting similar nucleotide sequences by comparing queries to reference databases with known function or taxonomy, commonly used in bioinformatics.

What is TetraBlaster?

TetraBlaster is a bioinformatics application used to perform sequence similarity searches to identify homologous sequences. It utilizes a heuristic algorithm to rapidly compare a query nucleotide or protein sequence against reference sequence databases such nucleotide (nt/nr), expressed sequence tags (EST), sequence tagged sites (STS), genomic survey sequences (GSS), high-throughput genomic sequences (HTGS), protein data bank (PDB), SwissProt, PIR, PRF, and custom user databases.

Key features of TetraBlaster include:

• Fast heuristic search algorithms for rapid sequence comparisons
• Support for BLAST+ executables for nucleotide blastn, blastp, blastx, tblastn, and tblastx searches
• Automated retrieval of sequences from NCBI databases for up-to-date comparisons
• Customizable parameters for e-value, word size, match/mismatch scores etc.
• Filtering of results by length, similarity percentage or annotation
• Visualization of alignments, sequence descriptions, and genomic context
• Exporting results to text, HTML, XML formats

By rapidly scanning sequence databases for local alignments, TetraBlaster enables discoveries of sequence motifs, gene families, and functional domains shared between novel and previously characterized genes. It is a useful tool for functional inference, phylogenetic classification, and genomic annotation projects.

TetraBlaster Features

Official Links