Folding@home

Folding@home

Folding@home is a distributed computing project that uses volunteer computing power for disease research. It simulates protein folding to help researchers better understand diseases like Alzheimer's, Huntington's, Parkinson's disease, and many cancers.
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volunteer-computing disease-research protein-folding simulations

Folding@home: Volunteer-Driven Disease Research

Parkinson's disease, and many cancers with the help of distributed computing.

What is Folding@home?

Folding@home is a distributed computing project launched in 2000 by Vijay Pande and colleagues at Stanford University. It harnesses the unused processing power of personal computers owned by volunteers to simulate protein folding, computationally intensive molecular dynamics simulations of protein folding and misfolding.

The simulations run when a person's computer would otherwise be idle, allowing researchers to run very large numbers of simulations. The aggregate computing power provided by Folding@home project participants is formidable, regularly attaining performance levels of hundreds of petaflops. This computing power aids fundamental biomedical research that may dramatically improve people’s lives.

The primary focus of Folding@home is understanding protein folding as it relates to diseases, including Alzheimer’s disease, Huntington’s disease, Parkinson's disease, and many cancers. A deeper understanding of protein folding and misfolding enables the design of new drugs and therapies for these diseases.

Volunteers can download and run the Folding@home software when their computers are idle. No active participation is required once the software is installed. The program receives simulation data from Stanford, runs the simulations, and sends the results back to Stanford. Researchers analyze this data to study how proteins fold and misfold.

Folding@home Features

Features

  1. Distributed computing project
  2. Uses volunteer computing power
  3. Simulates protein folding
  4. Helps researchers understand diseases
  5. Supports research on Alzheimer's, Huntington's, Parkinson's, and many cancers

Pricing

  • Free

Pros

Contributes to important disease research

Allows anyone to participate and contribute computing power

Free to use

Helps advance scientific understanding of diseases

Cons

Requires users to have compatible hardware and software

May increase energy consumption and wear on user devices

Results may not directly benefit individual users


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