Parkinson's disease, and many cancers with the help of distributed computing.
Folding@home is a distributed computing project launched in 2000 by Vijay Pande and colleagues at Stanford University. It harnesses the unused processing power of personal computers owned by volunteers to simulate protein folding, computationally intensive molecular dynamics simulations of protein folding and misfolding.
The simulations run when a person's computer would otherwise be idle, allowing researchers to run very large numbers of simulations. The aggregate computing power provided by Folding@home project participants is formidable, regularly attaining performance levels of hundreds of petaflops. This computing power aids fundamental biomedical research that may dramatically improve people’s lives.
The primary focus of Folding@home is understanding protein folding as it relates to diseases, including Alzheimer’s disease, Huntington’s disease, Parkinson's disease, and many cancers. A deeper understanding of protein folding and misfolding enables the design of new drugs and therapies for these diseases.
Volunteers can download and run the Folding@home software when their computers are idle. No active participation is required once the software is installed. The program receives simulation data from Stanford, runs the simulations, and sends the results back to Stanford. Researchers analyze this data to study how proteins fold and misfold.
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