GlycoLeap

GlycoLeap

GlycoLeap is open-source software for analyzing glycoproteins and glycan structures. It can predict glycan structures from mass spectrometry data and model protein glycosylation.
GlycoLeap image
glycobiology mass-spectrometry glycoproteins glycan-analysis

GlycoLeap: Open-Source Glycan Structure Analysis Software

Predict glycan structures, model protein glycosylation, and analyze glycoproteins with this free software

What is GlycoLeap?

GlycoLeap is an open-source software tool developed for glycoinformatics and glycoproteomics research. It enables users to analyze, predict, and model glycan structures attached to proteins or glycoproteins.

Some key features of GlycoLeap include:

  • Prediction of glycan structures from mass spectrometry data using fragmentation modeling
  • Modeling and visualization of protein glycosylation
  • Glycan structure drawing and notation support
  • Glycosylation site prediction using machine learning
  • Glycan fragmentation simulation for predicting mass spectra
  • Integration with protein structure databases like PDB and UniProt

GlycoLeap is implemented in Java and can be run on Windows, Mac, and Linux systems. It provides an interactive user interface for designing workflows and visualizing results. The software is useful for glycobiology researchers seeking to characterize and study glycoproteins or model protein glycosylation computationally.

Overall, GlycoLeap is a feature-rich open-source application for glycoinformatics analysis and glycoproteomics research. With its GUI and workflow features, it makes computational analysis of glycans more accessible to researchers.

GlycoLeap Features

Features

  1. Predict glycan structures from MS/MS data
  2. Annotate glycopeptides from LC-MS/MS data
  3. Model protein glycosylation
  4. Visualize glycan structures
  5. Analyze glycan compositions

Pricing

  • Open Source

Pros

Open source and free to use

User friendly graphical interface

Supports common data formats

Integrates with other tools like GlycoWorkbench

Cons

Limited to glycoprotein and glycan analysis

Less advanced compared to commercial tools

Requires training to use effectively


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