What is PyMOL?
PyMOL is a popular open-source molecular visualization system created by Warren DeLano and currently maintained by Schrödinger. It is designed specifically for visualizing and animating 3D structures of small molecules and biological macromolecules such as proteins and nucleic acids.
Some key features and capabilities of PyMOL include:
- High-quality rendering and ray tracing for publication-ready images and movies
- Support for a wide range of molecular data file formats
- Interactive visualization with rotations, selections, coloring, etc.
- Measurement tools for distances, angles, surface areas, etc.
- Sequence and structure alignment capabilities
- Integrated Python scripting for automation and customization
- Plugins and library for advanced features like electrostatics and visualization of large structures
PyMOL can be used on Windows, Mac, and Linux systems. The intuitive GUI combined with flexible scripting has made it one of the most widely used platforms in molecular modeling, structural biology education, and molecular visualization in research publications and presentations.
Some alternatives with similar functionality include UCSF Chimera, VMD, Swiss PDB Viewer, and others. But PyMOL remains popular as a free tool for high-quality molecular graphics and flexible customization via scripting.