Circos

Circos

Circos is an open-source software used to visualize data in a circular layout. It is commonly used to explore relationships between genomic data such as DNA sequences, but can also visualize other types of complex data sets and networks.
Circos screenshot

Circos: Open-Source Data Visualization Software

Circos is an open-source software used to visualize data in a circular layout, commonly used for genomic data exploration and visualization of complex datasets and networks.

What is Circos?

Circos is an open-source software originally developed for visualizing genomic data. It creates circular layouts that can display relationships between data points and illustrate complex patterns across genomes. The key features of Circos include:

  • Circular ideograms for displaying genomic coordinates and data tracks.
  • Ribbons and links for connecting related data points across tracks and circular axes.
  • Scatter, line and histogram plots for showing quantitative data.
  • Heatmaps to represent matrices and display patterns in large data sets.
  • Flexible configuration using plain text files for designing complex visualizations without programming.
  • Publication-ready vector graphics output.

Circos visualizations help researchers gain insight into genomic similarities and structural variations across organisms. By arranging genomes/chromosomes around a circle and connecting related data points, Circos reveals syntenic relationships, rearrangements, conservation of genes or regulatory elements across species. It highlights variation, harmonization and concordance in the data. Circos facilitates the identification and analysis of translocations, inversions, fusions, conserved elements and more in an intuitive visualization.

Originally created for genomic data analysis, Circos has also been used for visualizing data networks in other fields like business analytics, social network analysis and more. The circular connectivity makes it easy to spot relationships in large, multidimensional data sets. Customized Circos plots can help reveal structure and patterns that are not apparent from looking at the raw data.

Circos Features

Features

  1. Visualizes data in a circular layout
  2. Can visualize connections between entities in large datasets
  3. Supports visualizing relationships between genomic data like DNA sequences
  4. Allows exploration of complex networks and relationships in data
  5. Highly customizable layout, colors, fonts, etc
  6. Can integrate with data from many formats like BED, GFF, SAM, etc
  7. Includes utilities for data analysis and manipulation
  8. Command-line and GUI versions available

Pricing

  • Open Source

Pros

Very flexible and customizable for visualizing many types of data

Powerful way to see connections and relationships in complex data

Widely used in genomics research and well supported

Open source with active development community

Integrates with many data sources and formats

Available on multiple platforms

Cons

Steep learning curve for configuration and customization

Visualizations can become cluttered with large or complex datasets

Limited built-in statistical analysis capabilities

Command-line version has a complex interface

Requires programming skills for advanced usage

Limited documentation and support resources

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