Genome

Genome

Genome is an open-source, integrated genome browser used for visualizing genomic data. It enables users to view and analyze genome assemblies and annotations, variation data, expression data, and epigenetic data in an interactive graphical interface.
Genome image
genomics visualization genome-browser

Genome: Open-Source Genome Browser

An integrated genome browser for visualizing genomic data, including genome assemblies, annotations, variation data, expression data, and epigenetic data in an interactive graphical interface.

What is Genome?

Genome is an open-source, integrated genome browser developed by the University of California, Santa Cruz for visualizing genomic data. It is used by geneticists, molecular biologists, and bioinformaticians to view and analyze genome assemblies and annotations. Key features of Genome include:

  • Interactive graphical interface for navigating genome assemblies down to the nucleotide level.
  • Support for viewing common genomic file formats such as BAM, BED, GFF/GTF, VCF, and BigWig.
  • Visualization of genomic features like genes, transcripts, variations, repeats, GC content, etc.
  • Options for aligning RNA-Seq and ChIP-Seq data to reference genomes.
  • Customizable tracks and configuration options for data analysis.
  • Session saving and sharing capabilities to enable collaboration.
  • Scriptability via a CustomTrack feature and API for programmatic access.

Genome is implemented in C++ and runs as a desktop application on Linux, Mac and Windows systems. It can be used standalone for small-scale analysis or integrated into larger bioinformatics pipelines and workflows. The open-source codebase enables community contributions to expand functionality over time.

Genome Features

Features

  1. Visualize genomic data
  2. View genome assemblies and annotations
  3. Analyze variation, expression and epigenetic data
  4. Interactive graphical interface
  5. Customizable tracks and display
  6. Support for common file formats
  7. Integrates with Galaxy workflow system

Pricing

  • Open Source
  • Free

Pros

Open source and free to use

User-friendly graphical interface

Support for wide range of data types

Active development community

Integrates well with other bioinformatics tools

Cons

Steep learning curve

Limited documentation and tutorials

Difficult to customize advanced features

Only supports command-line usage

Lacks some features of commercial browsers


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